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Sixty elderly men were put on various Ostarine dosages for 3 months, and it was found that simply taking 3mg of Ostarine per day led to an increase in muscle mass by 1.76-2.7 kg (4.1-5.2 lbs), whereas placebo increased muscle growth by 1.08-1.44 kg (2.5-3.2 lbs) (Boucher and Bouchard, 2006). Sulfur supplements have been recommended as a natural remedy for sarcopenia since the 19th century. The main component of sulfur comes from sulfur compounds and the sulfur is transported in the urine with water (Molotch et al., 1991; Sato et al., 1994; Cope et al., 2006; Pichiavelli et al., 2007). Although several supplements have been developed, the results of the study by Lutz et al. (2001) suggested that a mixture of sulfur and zinc is effective, and that sulfur has higher bioavailability than zinc (10-100%). This study also showed that sulfonates (Sulfite) had the highest bioavailability, and they were also well-developed. In another study by Lutz et al. (2002), the authors found that in 60 healthy subjects, an additional 300mg of sulfonate per day led to a small but steady increase in urinary sulfates (which increases to ~150 mg/day over the course of 4 months), which was not significantly different from placebo. This effect was not observed in a control group, with a relatively small increase (100-200mg/day) of sulfatase activity by placebo (Figure ). Although sulfur supplements are often recommended in elderly patients that have suffered from osteoporosis, these reports had not been verified in older volunteers. The results of the study by Lutz et al. (2002) suggested that Sulfite could be effective in elderly smokers. This study also mentioned that Sulfite has high bioavailability, and a lower absorption rate than zinc and sulphadiazine. Since sulfonates have the highest bioavailability of any supplements, they could be particularly beneficial in those patients who have been using smoking cessation methods such as smoking cessation medications or nicotine replacement devices, since they increase bioavailability because their solubility is reduced. It may even be difficult to find sulfonates in pharmacies in the United States, since they are classified as a dietary supplement. The most relevant published study on Sulfur supplements has been published a few years ago by Gubérez-Gonzalez et al. (2002). This study had previously examined the results of a clinical trial in healthy elderly volunteers. They Similar articles: